PKC ζ pseudosubstrate

Catalog # Availability Size / Price Qty
1791/1
PKC ζ pseudosubstrate
1 Image
Description: PKC ζ inhibitor peptide (attached to cell-permeable vector)
Alternative Names: Protein kinase C zeta pseudosubstrate
Product Details
Citations (2)
Reviews

Biological Activity

Inhibitor of protein kinase C (PKC) ζ; attached to cell permeabilisation Antennapedia domain vector peptide. Consists of amino acids 113 - 129 of PKC ζ pseudosubstrate domain linked by a disulphide bridge to the Antennapedia domain vector peptide. The Antennapedia peptide is actively taken up by intact cells, at 4 or 37°C, ensuring rapid and effective uptake of the inhibitor peptide. Once inside the cell, the disulphide bonds are subjected to reduction in the cytoplasm leading to release of the inhibitor peptide. Induces mast cell degranulation by a PKC ζ-independent pathway.

Technical Data

M.Wt:
4673.59
Formula:
C208H336N74O44S3
Sequence:
CRQIKIWFQNRRMKWKK CSIYRRGARRWRKLYRAN*

(Modifications: Disulfide bridge between 1 -1*)

Solubility:
Soluble to 2 mg/ml in water
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for PKC ζ pseudosubstrate

The citations listed below are publications that use Tocris products. Selected citations for PKC ζ pseudosubstrate include:

2 Citations: Showing 1 - 2

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