PM 226

Catalog # Availability Size / Price Qty
6220/10
PM 226 | CAS No. 1949726-13-9 | Cannabinoid R2/CB2 Agonists
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Description: Potent and selective CB2 receptor agonist; BBB permeable; neuroprotective

Chemical Name: 7-(1,1-Dimethylheptyl)-9-methoxy-4,4-dimethyl-4H-[1]benzopyrano[3,4-d]isoxazole

Purity: ≥98%

Product Details
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Biological Activity

Potent and selective CB2 receptor agonist (Ki = 12.8 nM; EC50 = 38.67 nM). Exhibits negligible affinity for the CB1 receptor (Ki > 40,000 nM) and no activity at the GPR55. Suppresses neuroinflammation by reducing microglial activation in a multiple sclerosis mouse model. BBB permeable; anti-inflammatory and neuroprotective.

Technical Data

M.Wt:
357.49
Formula:
C22H31NO3
Solubility:
Soluble in methyl acetate (supplied pre-dissolved -10mg/ml)
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
1949726-13-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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