PRDM16/MEL1 Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-77096PEP

Novus Biologicals
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Key Product Details

Source

Synthetic

Applications

Antibody Competition
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Product Specifications

Description

A blocking peptide containing 17 amino acids near the carboxy terminus of human PRDM16.

Source: Synthetic

(Accession #: CAH71530)

Application Notes

This peptide is useful as a blocking peptide for NBP1-77096.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-77096PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: PRDM16/MEL1

The reciprocal translocation t(1;3)(p36;q21) occurs in a subset of myelodysplastic syndrome (MDS) and acute myeloid leukemia (AML). This gene is located near the 1p36.3 breakpoint and has been shown to be specifically expressed in the t(1:3)(p36,q21)-positive MDS/AML. The protein encoded by this gene is a zinc finger transcription factor and contains an N-terminal PR domain. The translocation results in the overexpression of a truncated version of this protein that lacks the PR domain, which may play an important role in the pathogenesis of MDS and AML. Alternatively spliced transcript variants encoding distinct isoforms have been reported.

Long Name

PR Domain Containing 16

Alternate Names

MDS1/EVI1-like gene 1, MEL1, PFM13

Gene Symbol

Prdm16

Additional PRDM16/MEL1 Products

Product Documents for PRDM16/MEL1 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for PRDM16/MEL1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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