Catalog Number: 5135
Chemical Name: 3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide
Biological Activity
Red-fluorescent DNA stain. Membrane impermeant to live cells; differentiates between live and dead cells in cell populations.
Technical Data
  • M.Wt:
    668.39
  • Formula:
    C27H34I2N4
  • Solubility:
    Soluble to 5 mM in water with sonication
  • Purity:
    >95%
  • Storage:
    Store at -20°C
  • CAS No:
    25535-16-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.
    Jeong et al.
    J.Biol.Chem., 2013;289:4135
  2. p53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors.
    Sonnemann et al.
    Br.J.Cancer, 2014;110:656
  3. Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.
    Yun et al.
    J.Biol.Chem., 2013;289:1491

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