Propidium iodide
Chemical Name: 3,8-Diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide
Purity: ≥95%
Biological Activity
Red-fluorescent DNA stain. Membrane impermeant to live cells. Propidium iodide staining differentiates between live and dead cells in cell populations.Plan Your Experiments
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Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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SIRT4 protein suppresses tumor formation in genetic models of Myc-induced B cell lymphoma.
Jeong et al.
J.Biol.Chem., 2013;289:4135 -
p53-dependent and p53-independent anticancer effects of different histone deacetylase inhibitors.
Sonnemann et al.
Br.J.Cancer, 2014;110:656 -
Serine hydrolase inhibitors block necrotic cell death by preventing calcium overload of the mitochondria and permeability transition pore formation.
Yun et al.
J.Biol.Chem., 2013;289:1491
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Propidium Iodide was used as an intracellular fluorescent dye. Picture is of the glass electrode with a 5mM solution. 250uM was also tried but had poor visibility.
