Chemical Name:4-[3-(Phenylmethoxy)propyl]-1H-imidazole oxalate
Biological Activity High affinity histamine H3 receptor ligand (pKi = 8.62) that acts as a protean agonist at recombinant and native receptors. In functional studies, activity ranges from full agonist to inverse agonist depending on system used. Displays partial agonist effects on cAMP inhibition and MAPK activity, neutral antagonist activity on histamine release and partial inverse agonism of [3H]-arachidonic acid release.
Soluble to 100 mM in DMSO and to 100 mM in water
Desiccate at RT
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