Reversible, non-competitive inhibitor of threonine dehydrogenase (TDH) (IC50
~500 nM). Induces autophagy and inhibits cell proliferation in mouse embryonic stem (ES) cells.
Soluble to 50 mM in DMSO
Store at +4°C
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All Tocris products are intended for laboratory research use only.
Targeted killing of a mammalian cell based upon its specialized metabolic state.
Alexander et al.