Dehydrogenase Inhibitors: Products

GAPDH inhibitor; neuroprotective

Succinate dehydrogenase inhibitor

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

Inosine monophosphate dehydrogenase (IMPDH) inhibitor

PDH and KGDH inhibitor

Inosine monophosphatase dehydrogenase (IMPDH) inhibitor

High affinity 15-PGDH inhibitor; promotes hematopoiesis and hepatocyte proliferation

Malate dehydrogenase-2 (MDH2) inhibitor; also inhibits HIF-1α

Potent and selective inhibitor of mutant isocitrate dehydrogenase 1 (mIDH1)

Potent, reversible glucose-6-phosphate dehydrogenase (G6PD) inhibitor

MTHFD2 inhibitor

Potent inhibitor of mutant isocitrate dehydrogenase (mIDH1)

Potent and selective hydroxysteroid 17β dehydrogenase 13 (HSD17B13) inhibitor

IMPDH2 (inosine monophosphate dehydrogenase 2) inhibitor, also glioblastoma targeting Nicotinamide mimetic prodrug