Rizatriptan benzoate
Chemical Name: N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine benzoate
Purity: ≥99%
Biological Activity
Rizatriptan benzoate is a 5-HT1B/1D agonist. Antimigraine agent; attenuates effects of CGRP on light aversion in mice. Orally bioavailable.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT1B/D agonist.
Kaiser et al.
J.Neurosci., 2012;32:15439 -
Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors.
Street et al.
J.Med.Chem., 1995;38:1799
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