Chemical Name: N,N-Dimethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1H-indole-3-ethanamine benzoate
Biological Activity5-HT1B/1D agonist. Antimigraine agent; attenuates effects of CGRP on light aversion in mice. Orally bioavailable.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Modulation of CGRP-induced light aversion in wild-type mice by a 5-HT1B/D agonist.
Kaiser et al.
Synthesis and serotonergic activity of N,N-dimethyl-2-[5-(1,2,4-triazol-1-ylmethyl)-1H-indol-3-yl]ethylamine and analogues: potent agonists for 5-HT1D receptors.
Street et al.
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