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6 results for "5-HT1B Receptor Agonists" in Products
5-HT1B Receptor Agonists
5-HT1B is a 7TM receptor for serotonin and is expressed on striatal neurons and Purkinje cells in the cerebellum. 5-HT1B ligation inhibits glycinergic signaling, appetite, circadian rhythym light responsiveness, and trigeminal-mediated nociception. It is an important pharmacologic target in the treatment of migrane headaches.
5-HT1B agonist
| Chemical Name: | 1,4-Dihydro-3-(1,2,3,6-tetrahydro-4-pyridinyl)-5H-pyrrol[3,2-b]pyridin-5-one dihydrochloride |
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Potent and selective 5-HT1B agonist
| Chemical Name: | 5-Propoxy-3-(1,2,3,6-tetrahydro-4-pyridinyl)-1H-pyrrolo[3,2-b]pyridine hydrochloride |
| Purity: | ≥98% |
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5-HT1A, 5-HT1B and 5-HT1D agonist
| Alternate Names: | GR 43175 |
| Chemical Name: | 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide succinate |
| Purity: | ≥99% |
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5-HT1B agonist
| Chemical Name: | 7-Trifluoromethyl-4-(4-methyl-1-piperazinyl)pyrrolo[1,2-a]-quinoxaline dimaleate |
| Purity: | ≥98% |
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Highly potent 5-HT1B agonist; also 5-HT3 antagonist
| Chemical Name: | 6-Chloro-2-[piperidinyl-4-thio]pyridine hydrochloride |
| Purity: | ≥99% |
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Potent 5-HT1B/1D/1F agonist
| Chemical Name: | (4S)-4-((3-(2-(Dimethylamino)ethyl)-1H-indol-5-yl)methyl)-2-oxazolidinone |
| Purity: | ≥99% |
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