Ro 20-1724

  ( 2 citations )    
Product Datasheet
Catalog Number:0415
Chemical Name:4-(3-Butoxy-4-methoxyphenyl)methyl-2-imidazolidone
Product Details
Citations (2)
Reviews
Biological Activity
Widely used inhibitor of cyclic nucleotide phosphodiesterase, selective for PDE4 (IC50 = 2.0 μM). Also available as part of the Phosphodiesterase Inhibitor Tocriset™.
Technical Data
  • M.Wt:
    278.35
  • Formula:
    C15H22N2O3
  • Solubility:
    Soluble to 100 mM in ethanol and to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Store at RT
  • CAS No:
    29925-17-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Ro 20-1724 include:

2 Citations: Showing 1 - 2
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  1. Rapid remodeling of tight junctions during paracellular diapedesis in a human model of the blood-brain barrier.
    Authors: Winger Et al.
    J Immunol  2014;193:2427
  2. Phosphodiesterase 4 inhibition impairs cocaine-induced inhibitory synaptic plasticity and conditioned place preference.
    Authors: Zhong Et al.
    Neuropsychopharmacology  2012;37:2377

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