Rotigotine hydrochloride

Catalog # Availability Size / Price Qty
3896/10
3896/50
Dopamine D2 Receptor Agonists Small Molecule
1 Image
Description: D2 and D3 agonist
Alternative Names: N 0923

Chemical Name: (6S)-5,6,7,8-Tetrahydro-6-[propyl[2-(2-thienyl)ethyl]amino]-1-naphthalenol hydrochloride

Purity: ≥99%

Product Details
Citations (1)
Supplemental Products
Reviews

Biological Activity

Dopamine D2 and D3 receptor agonist. Ki values are 13 and 0.71 nM for D2 and D3 respectively. Also has significant affinity for 5-HT1A and adrenergic α2B receptors. Exhibits antiparkinsonian acitivity.

Technical Data

M.Wt:
351.93
Formula:
C19H25NOS.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥99%
Storage:
Desiccate at RT
CAS No:
125572-93-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. The in vitro receptor profile of rotigotine: a new agent for the treatment of Parkinson's disease.
    Scheller et al.
    Naunyn.Schmiedebergs.Arch.Pharmacol., 2009;379:73
  2. N-0923, a selective DA D2 receptor agonist, is efficacious in rat and monkey models of Parkinson's disease.
    Belluzzi et al.
    Mov.Disord., 2004;9:147

Product Datasheets

or select another batch:
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for Rotigotine hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Rotigotine hydrochloride include:

1 Citation: Showing 1 - 1

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Reviews for Rotigotine hydrochloride

There are currently no reviews for this product. Be the first to review Rotigotine hydrochloride and earn rewards!

Have you used Rotigotine hydrochloride?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.