Selective group I metabotropic glutamate receptor agonist which activates both mGlu1
. Also reported to be an antagonist at metabotropic glutamate receptors linked to phospholipase D. (S)-3,5-DHPG
(Cat. No. 0805) also available.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Other Product-Specific Information:
3,5-Dihydroxyphenylglycine: a potent agonist of metabotropic glutamate receptors.
Ito et al.
Regulation of phosphoinositide turnover in neonatal rat cerebral cortex by group I- and II-selective metabotropic glutamate receptor agonists.
Mistry et al.
The group I mGlu receptor agonist DHPG induces a novel form of LTD in the CA1 region of the hippocampus.
Palmer et al.
Pharmacological characterization of metabotropic glutamate recpetors coupled to phopholipase D in the rat hippocampus.
Pellegrini-Giampietro et al.
The citations listed below are publications that use Tocris products. Selected citations for (RS)-3,5-DHPG include:
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