SAHA

  ( 2 citations )    
Product Datasheet
Catalog Number:4652
Alternate Names:Vorinostat
Chemical Name:N-Hydroxy-N'-phenyloctanediamide
Product Details
Citations (2)
Reviews
Biological Activity
Inhibits Class I and II histone deacetylases (HDACs); induces accumulation of acetylated histones H2A, H2B, H3 and H4 in transformed cultured cells. Suppresses cell growth in a range of cancer cell lines; induces apoptosis in cutaneous T cell lymphoma cells in vitro. Activates autophagy.
Technical Data
  • M.Wt:
    264.32
  • Formula:
    C14H20N2O3
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    149647-78-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for SAHA include:

2 Citations: Showing 1 - 2
Filter your results:

  1. RAD51 interconnects between DNA replication, DNA repair and immunity.
    Authors: Bhattacharya Et al.
    Nucleic Acids Res  2017;45:4590
  2. Single-cell analysis reveals IGF-1 potentiation of inhibition of the TGF-β/Smad pathway of fibrosis in humankeratocytes in vitro
    Authors: Sarenac Et al.
    Scientific Reports  2016;6:34373

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs

Have you used SAHA?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee