SCH 39166 hydrobromide

  ( 4 citations )    
Product Datasheet
Catalog Number:2299
Alternate Names:Ecopipam hydrobromide
Chemical Name:(6aS-trans)-11-Chloro-6,6a,7,8,9,13b-hexahydro-7-methyl-5H-benzo[d]naphth[2,1-b]azepin-12-ol hydrobromide
Product Details
Citations (4)
Supplemental Products
Reviews
Biological Activity
High affinity dopamine D1/D5 receptor antagonist; displays Ki values of 1.2, 2, 980, 5520, 80 and 731 nM for binding to D1, D5, D2, D4, 5-HT and α2a receptors, respectively.
Technical Data
  • M.Wt:
    394.73
  • Formula:
    C19H20ClNO.HBr
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >99
  • Storage:
    Desiccate at RT
  • CAS No:
    1227675-51-5
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for SCH 39166 hydrobromide include:

4 Citations: Showing 1 - 4
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  1. Attenuated dopaminergic tone in the paraventricular nucleus contributing to sympathoexcitation in rats with Type 2 diabetes.
    Authors: Zheng Et al.
    Nat Commun  2014;306:R138
  2. RNAi-mediated silencing of MLL-AF9 reveals leukemia-associated downstream targets and processes.
    Authors: Fleischmann Et al.
    Mol Cancer  2014;13:27
  3. The dopamine D1 receptor is expressed and facilitates relaxation in airway smooth muscle.
    Authors: Mizuta Et al.
    Am J Physiol Regul Integr Comp Physiol  2013;14:89
  4. Cannabinoid CB1 antagonists and dopamine antagonists produce different effects on a task involving response allocation and effort-related choice in food-seeking behavior.
    Authors: Sink Et al.
    Psychopharmacology (Berl)  2008;196:565

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