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Catalog Number:3708
Alternate Names:scPanx
Chemical Name:
Product Details
Citations (1)
Supplemental Products
Reviews
Biological Activity
Scrambled version of 10Panx (Cat. No. 3348), a Panx-1 mimetic inhibitory peptide that blocks pannexin-1 gap junctions, inhibits P2X7-mediated dye uptake, ATP-mediated IL-1β release and caspase-1 activation without altering membrane current in macrophages in vitro. 10Panx also blocks activation of NMDA receptor secondary currents (I2nd) by > 70%.
Scrambled version of 10Panx (Cat. No. 3348), a Panx-1 mimetic inhibitory peptide that blocks pannexin-1 gap junctions, inhibits P2X7-mediated dye uptake, ATP-mediated IL-1β release and caspase-1 activation without altering membrane current in macrophages in vitro. 10Panx also blocks activation of NMDA receptor secondary currents (I2nd) by > 70%.
Technical Data
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M.Wt:1242.37
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Formula:C58H79N15O16
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Sequence:FSVYWAQADR
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Solubility:Soluble to 0.50 mg/ml in water
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Storage:Store at -20°C
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CAS No:1315378-72-3
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Product Datasheets
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Citations:
The citations listed below are publications that use Tocris products. Selected citations for Scrambled 10Panx include:
1 Citations: Showing 1 - 1
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