Scrambled 10Panx

  ( 1 citations )    
Product Datasheet
Catalog Number:3708
Alternate Names:scPanx
Chemical Name:
Product Details
Citations (1)
Supplemental Products
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Biological Activity
Scrambled version of 10Panx (Cat. No. 3348), a Panx-1 mimetic inhibitory peptide that blocks pannexin-1 gap junctions, inhibits P2X7-mediated dye uptake, ATP-mediated IL-1β release and caspase-1 activation without altering membrane current in macrophages in vitro. 10Panx also blocks activation of NMDA receptor secondary currents (I2nd) by > 70%.
Technical Data
  • M.Wt:
    1242.37
  • Formula:
    C58H79N15O16
  • Sequence:
    FSVYWAQADR
  • Solubility:
    Soluble to 0.50 mg/ml in water
  • Storage:
    Store at -20°C
  • CAS No:
    1315378-72-3
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Scrambled 10Panx include:

1 Citations: Showing 1 - 1

  1. The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain.
    Authors: Albalawi Et al.
    Front Cell Neurosci  2017;11:227

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