Spiperone hydrochloride

Key Product Details

Product Description

Spiperone hydrochloride is a 5-HT_2A serotonin and selective D₂-like dopamine receptor antagonist (K_i values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D₂, D₃, D₄, D₁ and D₅ receptors respectively). Antipsychotic.

Product Specifications for Spiperone hydrochloride

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for Spiperone hydrochloride

The following data is based on the product molecular weight 431.94.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	2.32 mL	11.58 mL	23.15 mL
5 mM	0.46 mL	2.32 mL	4.63 mL
10 mM	0.23 mL	1.16 mL	2.32 mL
50 mM	0.05 mL	0.23 mL	0.46 mL

Calculators

Background References

References are publications that support the biological activity of the product.

• Seeman and van Tol DA receptor pharmacology. TiPS 1994 PMID: 7940991
• Hoyer VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin). Pharmacol.Rev. 1994 PMID: 7938165

Product Documents for Spiperone hydrochloride