Spiperone hydrochloride

Catalog # Availability Size / Price Qty
0995/50
Spiperone hydrochloride | CAS No. 2022-29-9 | 5-HT2A Receptor Antagonists
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Description: 5-HT2A antagonist; also D2-like antagonist

Chemical Name: 8-[4-(4-Fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one hydrochloride

Purity: ≥98%

Product Details
Citations (6)
Supplemental Products
Reviews

Biological Activity

5-HT2A serotonin and selective D2-like dopamine receptor antagonist (Ki values are 0.06, 0.6, 0.08, ~ 350, ~ 3500 nM for D2, D3, D4, D1 and D5 receptors respectively). Antipsychotic.

Technical Data

M.Wt:
431.94
Formula:
C23H26FN3O2.HCl
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at RT
CAS No:
2022-29-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. VII. International Union of Pharmacology classification of receptors for 5-hydroxytryptamine (serotonin).
    Hoyer et al.
    Pharmacol.Rev., 1994;46:157
  2. DA receptor pharmacology.
    Seeman and Van Tol
    Trends Pharmacol.Sci., 1994;15:264

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Citations for Spiperone hydrochloride

The citations listed below are publications that use Tocris products. Selected citations for Spiperone hydrochloride include:

6 Citations: Showing 1 - 6

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