SR 27897

Tocris Bioscience | Catalog # 2190

Potent and selective CCK1 antagonist
Tocris Bioscience

Key Product Details

Description

Potent and selective CCK1 antagonist

Alternative Names

Lintitript
View all CCK1 Receptor Antagonists »

Product Description

SR 27897 is a potent, non-peptide CCK1 receptor antagonist that displays > 33-fold selectivity over CCK2 receptors (EC50 values are 6 and 200 nM respectively). Causes an increase in plasma leptin levels and increases food intake in rats in vivo.

Product Specifications for SR 27897

Molecular Weight

411.86

Formula

C20H14ClN3O3S

Storage

Store at +4°C

Purity

≥98% (HPLC)

Chemical Name

2-[[[4-(2-Chlorophenyl)-2-thiazolyl]amino]carbonyl]-1H-indole-1-acetic acid

CAS Number

136381-85-6

PubChem ID

122077

InChI Key

ILNRQFBVVQUOLP-UHFFFAOYSA-N

SMILES

OC(=O)CN1C(=CC2=CC=CC=C12)C(=O)NC1=NC(=CS1)C1=CC=CC=C1Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 20.59 50

Preparing Stock Solutions for SR 27897

The following data is based on the product molecular weight 411.86.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
0.5 mM 4.86 mL 24.28 mL 48.56 mL
2.5 mM 0.97 mL 4.86 mL 9.71 mL
5 mM 0.49 mL 2.43 mL 4.86 mL
25 mM 0.10 mL 0.49 mL 0.97 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 14 publications citing the usage of this product.

Product Documents for SR 27897

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for SR 27897

For research use only

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