Substance P

  ( 11 citations )    
Product Datasheet
Catalog Number:1156
Chemical Name:
Product Details
Citations (11)
Supplemental Products
Reviews
Biological Activity
Sensory neuropeptide and inflammatory mediator. Exerts excitatory effects on central and peripheral neurons, constricts bronchioles and is involved in pain transmission.
Technical Data
  • M.Wt:
    1347.6
  • Formula:
    C63H98N18O13S
  • Sequence:
    RPKPQQFFGLM

    (Modifications: Met-11 = C-terminal amide)

  • Solubility:
    Soluble to 0.80 mg/ml in water
  • Storage:
    Desiccate at -20°C
  • CAS No:
    33507-63-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets
COA view current batch
or select another batch:
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Substance P include:

11 Citations: Showing 1 - 10
Filter your results:

  1. Retromer stops beta-arrestin 1 mediated signaling from internalized cannabinoid 2 receptors.
    Authors: Nogueras-Ortiz
    Mol Biol Cell  2017;28(24):3554
  2. Increased CCN2, substance P and tissue fibrosis are associated with sensorimotor declines in a rat model of repetitive overuse injury.
    Authors: Fisher Et al.
    J Cell Commun Signal  2015;9:37
  3. μ-Opioid receptor inhibition of substance P release from primary afferents disappears in neuropathic pain but not inflammatory pain.
    Authors: Chen Et al.
    Neuroscience  2014;267:67
  4. Long-term potentiation of excitatory synaptic strength in spinothalamic tract neurons of the rat spinal cord.
    Authors: Hur and Park
    Korean J Physiol Pharmacol  2013;17:553
  5. Investigation of the functional expression of purine and pyrimidine receptors in porcine isolated pancreatic arteries.
    Authors: Alsaqati Et al.
    Purinergic Signal  2013;10:241
  6. Evidence for regulatory diversity and auto-regulation at the TAC1 locus in sensory neurones.
    Authors: Shanley Et al.
    J Neurosci  2011;8:10
  7. Investigating the effect of emetic compounds on chemotaxis in Dictyostelium identifies a non-sentient model for bitter and hot tastant research.
    Authors: Robery Et al.
    PLoS One  2011;6:e24439
  8. Activation of glycogen synthase kinase-3 β is required for hyperdopamine and D2 receptor-mediated inhibition of synaptic NMDA receptor function in the rat prefrontal cortex.
    Authors: Li Et al.
    J Neurosci  2009;29:15551
  9. A homogeneous fluorescent live-cell assay for measuring 7-transmembrane receptor activity and agonist functional selectivity through β-arrestin recruitment.
    Authors: Hanson Et al.
    Antioxid Redox Signal  2009;14:798
  10. Substance P selectively decreases paired pulse depression in the rat hippocampal slice.
    Authors: Wease and Davies
    BMC Neurosci  2005;6:66
  11. Role of neurokinin 3 receptors in supraoptic vasopressin and oxytocin neurons.
    Authors: Howe Et al.
    J Biomol Screen  2004;24:10103
Expand to show all Citations

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Have you used Substance P?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee