Substance P
Tocris Bioscience | Catalog # 1156
Sensory neuropeptide; inflammatory mediator
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Key Product Details
Description
Sensory neuropeptide; inflammatory mediator
Product Description
Substance P is a sensory neuropeptide and inflammatory mediator. Exerts excitatory effects on central and peripheral neurons, constricts bronchioles and is involved in pain transmission.
Product Specifications for Substance P
Molecular Weight
1347.60
Formula
C63H98N18O13S
Storage
Store at -20°C
Purity
≥95% (HPLC)
CAS Number
33507-63-0
PubChem ID
36511
InChI Key
ADNPLDHMAVUMIW-CUZNLEPHSA-N
SMILES
[H]N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCCN)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)N[C@@H](CC1=CC=CC=C1)C(=O)NCC(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCSC)C(N)=O
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
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Solubility
| Solubility | Soluble to 0.8mg/ml in water |
Calculators
Background References
References are publications that support the biological activity of the product. See our Citations tab to view 130 publications citing the usage of this product.
- Pernow Substance P. Pharmacol.Rev. 1983 PMID: 6196797
- Walsh Substance P-induced inflammatory responses in guinea-pig skin: the effect of specific NK1 receptor antagonists and the role of endogenous mediators. Br.J.Pharmacol. 1995 PMID: 7541689
- Andoh Substance P induction of itch-associated response mediated by cutaneous NK1 tachykinin receptors in mice. J.Pharmacol.Exp.Ther. 1998 PMID: 9732370
Product Documents for Substance P
Certificate of Analysis
To download a Certificate of Analysis, please enter a lot or batch number in the search box below.
Product Specific Notices for Substance P
For research use only
Citations for Substance P
Customer Reviews for Substance P (1)
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Assay Type: In VitroCell Line/Tissue: mast cellsVerified Customer | Posted 05/30/2018Used to stimulate mast cells to degranulate.
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