Tamsulosin hydrochloride

Tocris Bioscience | Catalog # 3050

Selective α1A antagonist
Tocris Bioscience

Key Product Details

Description

Selective α1A antagonist
View all Adrenergic alpha-1 Receptor Antagonists »

Product Description

Tamsulosin hydrochloride is a selective α1A-adrenoceptor antagonist (pKi values are 9.97, 9.64 and 8.86 for α1A, α1B and α1D subtypes respectively). Decreases resting maximal urethral pressure with negligible effect on mean arterial blood pressure in vivo.

Product Specifications for Tamsulosin hydrochloride

Molecular Weight

444.97

Formula

C20H28N2O5S.HCl

Storage

Desiccate at RT

Purity

≥98% (HPLC)

Chemical Name

5-[(2R)-2-[[2-(2-Ethoxyphenoxy)ethyl]amino]propyl]-2-methoxybenzenesulfonamide hydrochloride

CAS Number

106463-17-6

PubChem ID

5362376

InChI Key

ZZIZZTHXZRDOFM-XFULWGLBSA-N

SMILES

C[C@@H](NCCOC2=CC=CC=C2OCC)CC1=CC=C(OC)C(S(=O)(N)=O)=C1.Cl

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
water 4.45 10
DMSO 44.5 100

Preparing Stock Solutions for Tamsulosin hydrochloride

The following data is based on the product molecular weight 444.97.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.25 mL 11.24 mL 22.47 mL
5 mM 0.45 mL 2.25 mL 4.49 mL
10 mM 0.22 mL 1.12 mL 2.25 mL
50 mM 0.04 mL 0.22 mL 0.45 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 3 publications citing the usage of this product.

Product Documents for Tamsulosin hydrochloride

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tamsulosin hydrochloride

For research use only

Citations for Tamsulosin hydrochloride

Customer Reviews for Tamsulosin hydrochloride (1)

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  • Used to investigate cell metabolism
    Name: Anonymous
    Species: Rat
    Assay Type: In Vitro
    Cell Line/Tissue: Primary hippocampal neurons
    Verified Customer | Posted 01/27/2023
    The drug was incubated at 10 μM to investigate a potential effect on cell metabolism.

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