TCN 238

Discontinued Product

4259 has been discontinued.
View all Group III mGluR Modulators products.
TCN 238 | CAS No. 125404-04-8 | Group III mGluR Modulators
1 Image
Description: Positive allosteric modulator of mGlu4 receptors

Chemical Name: (E)-4-(2-Phenylethenyl)-2-pyrimidinamine

Purity: ≥98%

Product Details
Citations (1)

Biological Activity

TCN 238 is a positive allosteric modulator of mGlu4 receptors (EC50 = 1.0 μM for human and rat mGlu4 receptors). Orally available and brain penetrant.

Technical Data

Soluble to 100 mM in DMSO and to 10 mM in ethanol
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.


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*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

Citation for TCN 238

The citations listed below are publications that use Tocris products. Selected citations for TCN 238 include:

1 Citation: Showing 1 - 1


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