TCN 238

Catalog # Availability Size / Price Qty
4259/10
4259/50
Group III mGluR Modulators Small Molecule
1 Image
Description: Positive allosteric modulator of mGlu4 receptors

Chemical Name: (E)-4-(2-Phenylethenyl)-2-pyrimidinamine

Purity: ≥98%

Product Details
Citations (1)
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Biological Activity

Positive allosteric modulator of mGlu4 receptors (EC50 = 1.0 μM for human and rat mGlu4 receptors). Orally available and brain penetrant.

Technical Data

M.Wt:
197.24
Formula:
C12H11N3
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
125404-04-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for TCN 238

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