Selective inhibitor of histone deacetylase 6 (HDAC6). Inhibits HCT116 growth in combination with taxol
(Cat. No. 1097). Also inhibits growth of MCF-7 cells stimulated by estrogen.
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Design, synthesis, structure-selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors.
Itoh et al.