TCS HDAC6 20b
Chemical Name: 2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[220.127.116.11,7]dec-1-ylamino)heptyl] ester
Biological ActivitySelective inhibitor of histone deacetylase 6 (HDAC6). Inhibits HCT116 growth in combination with taxol (Cat. No. 1097). Also inhibits growth of MCF-7 cells stimulated by estrogen.
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Design, synthesis, structure-selectivity relationship, and effect on human cancer cells of a novel series of histone deacetylase 6-selective inhibitors.
Itoh et al.
Citation for TCS HDAC6 20b
The citations listed below are publications that use Tocris products. Selected citations for TCS HDAC6 20b include:
1 Citation: Showing 1 - 1
Acetylated α-Tubulin Regulated by N-Acetyl-Seryl-Aspartyl-Lysyl-Proline(Ac-SDKP) Exerts the Anti-fibrotic Effect in Rat Lung Fibrosis Induced by Silica.
Authors: Xiaojun Et al.
Sci Rep 2016;6:32257
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