TCS HDAC6 20b

Tocris Bioscience | Catalog # 4805

Selective HDAC6 inhibitor
Tocris Bioscience
Discontinued Product
4805 has been discontinued. View all Class II Histone Deacetylases Inhibitors products.

Key Product Details

Description

Selective HDAC6 inhibitor
View all Class II Histone Deacetylases Inhibitors »

Product Description

TCS HDAC6 20b is a selective inhibitor of histone deacetylase 6 (HDAC6). Inhibits HCT116 growth in combination with taxol (Cat. No. 1097). Also inhibits growth of MCF-7 cells stimulated by estrogen.

Product Specifications for TCS HDAC6 20b

Molecular Weight

480.70

Formula

C26H44N2O4S

Storage

Store at -20°C

Purity

≥98% (HPLC)

Chemical Name

2-Methylpropanethioic acid-S-[(6S)-6-[[(1,1-dimethylethoxy)carbonyl]amino]-7-oxo-7-(tricyclo[3.3.1.13,7]dec-1-ylamino)heptyl] ester

CAS Number

956154-63-5

PubChem ID

23636017

InChI Key

DQZMLPMCOMRJOR-MOVGKWKRSA-N

SMILES

O=C([C@@H](NC(OC(C)(C)C)=O)CCCCCSC(C(C)C)=O)NC1(CC3C2)CC(C3)CC2C1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 48.07 100
Ethanol 48.07 100

Preparing Stock Solutions for TCS HDAC6 20b

The following data is based on the product molecular weight 480.70.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 2.08 mL 10.40 mL 20.80 mL
5 mM 0.42 mL 2.08 mL 4.16 mL
10 mM 0.21 mL 1.04 mL 2.08 mL
50 mM 0.04 mL 0.21 mL 0.42 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 4 publications citing the usage of this product.

Product Documents for TCS HDAC6 20b

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for TCS HDAC6 20b

For research use only

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