Antitumor agent; promotes and stabilizes tubulin polymerization, causing cell cycle arrest. Induces autocatalytic activation of caspase-10 in CCRF-HSB-2 cells, triggering apoptosis.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Kishimoto T et al.
Leucocyte Typing VI. Garland Publishing Inc. London.
Taxol: a novel investigational antimicrotubule agent.
Rowinsky et al.
J.Natl.Cancer Inst., 1990;82:1247
Taxol: a unique antineoplastic agent with significant activity in advanced ovarian epithelial neoplasms.
McGuire et al.
Taxol induces caspase-10-dependent apoptosis.
Park et al.
Characterization of the taxol binding site on the microtubule.
Rao et al.
The citations listed below are publications that use Tocris products. Selected citations for Taxol include:
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