TCS JNK 6o

   
Product Datasheet
Catalog Number:3222
Chemical Name:N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide
Product Details
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Biological Activity
ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). Displays > 1000 fold selectivity over other kinases, including ERK2 and p38. Inhibits c-Jun phosphorylation (EC50 = 920 nM) and prevents collagen-induced platelet aggregation in vitro.
Technical Data
  • M.Wt:
    356.38
  • Formula:
    C18H20N4O4
  • Solubility:
    Soluble to 100 mM in DMSO
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    894804-07-0
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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