TCS JNK 6o

Catalog # Availability Size / Price Qty
3222/10
3222/50
TCS JNK 6o | CAS No. 894804-07-0 | JNK/c-jun Inhibitors
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Description: Selective JNK inhibitor

Chemical Name: N-(4-Amino-5-cyano-6-ethoxy-2-pyridinyl)-2,5-dimethoxybenzeneacetamide

Purity: ≥98%

Product Details
Citations (3)
Reviews

Biological Activity

ATP-competitive c-Jun N-terminal kinase (JNK) inhibitor (IC50 values are 2, 4 and 52 nM for JNK1, JNK2 and JNK3 respectively). Displays > 1000 fold selectivity over other kinases, including ERK2 and p38. Inhibits c-Jun phosphorylation (EC50 = 920 nM) and prevents collagen-induced platelet aggregation in vitro.

Technical Data

M.Wt:
356.38
Formula:
C18H20N4O4
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
894804-07-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citations for TCS JNK 6o

The citations listed below are publications that use Tocris products. Selected citations for TCS JNK 6o include:

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