Catalog Number: 3082
Chemical Name: 1-Oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine
Biological Activity
Superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects.
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. The superoxide scavenger TEMPOL induces urokinase receptor (uPAR) expression in human prostate cancer cells.
    Francis and Sehgal
    Mol.Cancer, 2006;5:21
  2. Neuroprotective effect of tempol, a catalytic scavenger of peroxynitrite-derived free radicals, in a mouse traumatic brain injury model.
    Deng-Bryant et al.
    J.Cereb.Blood Flow Metab., 2008;28:1114
  3. TEMPOL, a membrane-permeable radical scavenger, attenuates peroxynitrite- and superoxide anion-enhanced carrageenan-induced paw edema and hyperalgesia: a key role for superoxide anion.
    EurJ.Pharmacol., 2006;548:167
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