Tempol

Tocris Bioscience | Catalog # 3082

Superoxide scavenger; antioxidant
Tocris Bioscience

Key Product Details

Description

Superoxide scavenger; antioxidant
View all Additional Antioxidant Compounds »

Product Description

Tempol is a superoxide scavenger that displays neuroprotective, anti-inflammatory and analgesic effects. Tempol reduces γ-radiation-induced damage in hematopoietic stem cells in vitro and in vivo.

Product Specifications for Tempol

Molecular Weight

172.24

Formula

C9H18NO2

Storage

Store at -20°C

Purity

≥98%

Chemical Name

1-Oxyl-2,2,6,6-tetramethyl-4-hydroxypiperidine

CAS Number

2226-96-2

PubChem ID

137994

InChI Key

UZFMOKQJFYMBGY-UHFFFAOYSA-N

SMILES

CC1(C)CC(O)CC(C)(C)N1[O]

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Solvent Max Conc. mg/mL Max Conc. mM
Solubility
DMSO 17.22 100
Ethanol 17.22 100

Preparing Stock Solutions for Tempol

The following data is based on the product molecular weight 172.24.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

Concentration / Solvent Volume / Mass 1 mg 5 mg 10 mg
1 mM 5.81 mL 29.03 mL 58.06 mL
5 mM 1.16 mL 5.81 mL 11.61 mL
10 mM 0.58 mL 2.90 mL 5.81 mL
50 mM 0.12 mL 0.58 mL 1.16 mL

Calculators

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Background References

References are publications that support the biological activity of the product. See our Citations tab to view 52 publications citing the usage of this product.

Product Documents for Tempol

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Product Specific Notices for Tempol

For research use only

Customer Reviews for Tempol (1)

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  • Tempol blunts 15d-PGJ2-induced ROS levels in HL-1 cardiomyocytes
    Name: Chintan Koyani
    Species: Mouse
    Assay Type: In Vitro
    Cell Line/Tissue: HL-1 cardiomyocytes
    Verified Customer | Posted 10/13/2018
    HL-1 cardiomyocytes were incubated with Tempol (1 mM) for 30 min prior to 15d-PGJ2 treatments (15 μM) for 1 h to follow ROS generation using carboxy-H2DCFDA (10 μM). Figure shows that the antioxidant Tempol (a cell-permeable superoxide anion scavenger) blunted 15d-PGJ2-induced ROS formation efficiently.
    Tempol 3082

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