Catalog Number: 3813
Chemical Name: (1S,3aS,3bS,5aR,9aR,9bS,11aS)-6,9a,11a-Trimethyl-7-oxo-N-[2-(trifluoromethyl)phenyl]-2,3,3a,3b,4,5,5a,9b,10,11-decahydro-1H-indeno[5,4-f]quinoline-1-carboxamide
Biological Activity
Potent selective androgen receptor modulator (SARM) (IC50 = 30 nM). Steroidal compound. Exhibits limited effects on reproductive tissues and sebaceous glands; does not repress AP-1-sensitive MMP-1 reporter. Inhibits 5α-reductase type I and II (IC50 values are 2 and 3 nM respectively).
Technical Data
  • M.Wt:
    474.56
  • Formula:
    C27H33F3N2O2
  • Solubility:
    Soluble to 10 mM in DMSO and to 10 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at RT
  • CAS No:
    188589-61-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Identification of anabolic selective androgen receptor modulators with reduced activities in reproductive tissues and sebaceous glands.
    Schmidt et al.
    J.Biol.Chem., 2009;284:36367

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