Chemical Name: 4-[(6-Aminohexyl)oxy]-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione hydrochloride
Biological ActivityThalidomide 4'-ether-alkylC6-amine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand plus a C6 alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTACs R&D.
This product has been recently renamed. The previous name for this product was Thalidomide - linker 4
Please contact us for SD files of our available Degrader Building Blocks.
PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.
Usage GuidelinesThis product is provided for use in onward chemistry. Suitable solvents can be used.
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
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The dTAG system for immediate and target-specific protein degradation.
Nabet et al.
Transcription control by the ENL YEATS domain in acute leukaemia.
Erb et al.
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