Catalog Number: 1812
Alternate Names: Ritalin
Chemical Name: Threo-methyl α-Phenyl-2-piperidineacetate hydrochloride
Biological Activity
Psychomotor stimulant. Inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin. Increases locomotor activity in vivo.
Technical Data
  • M.Wt:
    269.77
  • Formula:
    C14H19NO2.HCl
  • Solubility:
    Soluble to 50 mM in water and to 100 mM in ethanol
  • Purity:
    >99%
  • Storage:
    Store at RT
  • CAS No:
    298-59-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Methylphenidate (Ritalin): behavioral studies in the rat.
    Askenasy et al.
    Int.J.Neurosci., 2007;117:757
  2. Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects.
    Leonard et al.
    Human Psychopharm., 2004;19:151
Citations:

The citations listed below are publications that use Tocris products. Selected citations for Threo-methylphenidate hydrochloride include:

2 Citations: Showing 1 - 2
Filter your results:

  1. Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics.
    Authors: Poulin Et al.
    Mol Pharmacol 2014;86:378
  2. Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish.
    Authors: Parker Et al.
    PLoS One 2014;231:2671

Have you used Threo-methylphenidate hydrochloride?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Note:

Contact Information

Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee

or select another batch: 

Feedback

Customer Information