Chemical Name: Threo-methyl α-Phenyl-2-piperidineacetate hydrochloride
Biological ActivityThreo-methylphenidate hydrochloride is a psychomotor stimulant. Inhibitor of dopamine and noradrenalin transporters that increases the extracellular concentration of dopamine and noradrenalin. Increases locomotor activity in vivo.
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Tocris products are intended for laboratory research use only, unless stated otherwise.
Methylphenidate (Ritalin): behavioral studies in the rat.
Askenasy et al.
Methylphenidate: a review of its neuropharmacological, neuropsychological and adverse clinical effects.
Leonard et al.
Human Psychopharm., 2004;19:151
Citations for Threo-methylphenidate hydrochloride
The citations listed below are publications that use Tocris products. Selected citations for Threo-methylphenidate hydrochloride include:
3 Citations: Showing 1 - 3
Pharmacological Chaperones of the DA Transporter Rescue DA Transporter Deficiency Syndrome Mutations in Heterologous Cells.
Authors: Beerepoot Et al.
J Biol Chem 2016;291:22053
Fluoxetine blocks Nav1.5 channels via a mechanism similar to that of class 1 antiarrhythmics.
Authors: Poulin Et al.
Mol Pharmacol 2014;86:378
Atomoxetine reduces anticipatory responding in a 5-choice serial reaction time task for adult zebrafish.
Authors: Parker Et al.
PLoS One 2014;231:2671
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