TMS

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TMS | CAS No. 24144-92-1 | Cytochrome P450 Inhibitors
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Description: Cytochrome P450 1B1 inhibitor
Alternative Names: (E)-2,3',4,5'-tetramethoxystilbene

Chemical Name: 1-[2,(3,5-Dimethoxyphenyl)ethenyl]-2,4-dimethoxybenzene

Product Details
Citations (1)
Reviews

Biological Activity

Potent, selective and competitive inhibitor of cytochrome P450 1B1, an enzyme overexpressed in certain tumors (IC50 = 6 nM). 50- and 520-fold selective over P450 1A1 and 1A2 respectively. Inhibits cancer cell growth in vitro.

Technical Data

Formula:
C18H20O4
Solubility:
Soluble to 25 mM in ethanol and to 100 mM in DMSO
Storage:
Store the unopened product at room temperature. Do not use past expiration date.
CAS No:
24144-92-1

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citation for TMS

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