TPEN

   
Product Datasheet
Catalog Number:4309
Chemical Name:N,N,N',N'-Tetrakis(2-pyridylmethyl)ethylenediamine
Product Details
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Biological Activity
Heavy metal chelator. Reacts with both Zn-proteome and Zn-metallothionein (MT) in LLC-PK1 cells; acts as an intracellular chelator of proteomic Zn2+. Activity decreases intracellular zinc levels, and induces apoptosis in HeLa and cultured human retinal pigment epithelium (RPE) cells. Cell permeable.
Technical Data
  • M.Wt:
    424.54
  • Formula:
    C26H28N6
  • Solubility:
    Soluble to 25 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    16858-02-9
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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