Catalog Number: 6002
Chemical Name: 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid
Biological Activity
Antioxidant vitamin E derivative; suppresses osteoclast formation and inhibits IL-1-induced osteoclast bone loss. Cell-permeable and water soluble.
Technical Data
  • M.Wt:
    250.29
  • Formula:
    C14H18O4
  • Solubility:
    Soluble to 100 mM in DMSO and to 100 mM in ethanol
  • Purity:
    >98%
  • Storage:
    Store at +4°C
  • CAS No:
    53188-07-1
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Inhibition of protein radical reactions of ferrylmyoglobin by the water-soluble analog of vitamin E, Trolox C.
    Giulivi et al.
    Arch.Biochem.Biophys., 1993;303:152
  2. Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling.
    Lee et al.
    J.Biol.Chem., 2009;284:13725
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