Valinomycin

  ( 1 citations )    
Product Datasheet
Catalog Number:3373
Chemical Name:Cyclo(D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl-D-α-hydroxyisovaleryl-D-valyl-L-lactoyl-L-valyl)
Product Details
Citations (1)
Reviews
Biological Activity
Selective K+ ionophore (K0.5 values are 48, 73, 75, 93 and 246 mM for K+, Rb+, Cs+, Na+ and Li+ respectively) that transports K+ across biological and artificial lipid membranes. Inhibits Ca2+-ATPase activity and induces apoptosis through mitochondrial membrane depolarization, caspase-3 activation and phosphatidylserine translocation in vitro.
Technical Data
  • M.Wt:
    1111.32
  • Formula:
    C54H90N6O18
  • Solubility:
    Soluble to 25 mM in DMSO and to 25 mM in ethanol
  • Storage:
    Desiccate at -20°C
  • CAS No:
    2001-95-8
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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Citations:

The citations listed below are publications that use Tocris products. Selected citations for Valinomycin include:

1 Citations: Showing 1 - 1

  1. SB-224289 Antagonizes the Antifungal Mechanism of the Marine Depsipeptide Papuamide A.
    Authors: Cassilly Et al.
    J Cancer  2016;11:e0154932

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