VEGF 165 Antibody (R012) - Azide and BSA Free

Novus Biologicals | Catalog # NBP2-89779

Recombinant Monoclonal Antibody
Novus Biologicals
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Key Product Details

Species Reactivity

Human, Cynomolgus Monkey

Applications

Neutralization

Label

Unconjugated

Antibody Source

Recombinant Monoclonal Rabbit IgG Clone # R012 expressed in HEK293

Format

Azide and BSA Free
View all VEGF 165 Primary Antibodies »

Product Specifications

Immunogen

This antibody was obtained from a rabbit immunized with purified, recombinant Human/Cynomolgus VEGF 165 (Uniprot#: P15692-4; Met1-Arg191)

Specificity

Has cross-reactivity in ELISA with: Mouse VEGF164Rat VEGF164

Clonality

Monoclonal

Host

Rabbit

Isotype

IgG

Description

This antibody can be stored at 2C-8C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20C to -80C. Avoid repeated freeze-thaw cycles.

Scientific Data Images for VEGF 165 Antibody (R012) - Azide and BSA Free

Neutralization: VEGF 165 Antibody (R012) [NBP2-89779]

Neutralization: VEGF 165 Antibody (R012) [NBP2-89779]

Neutralization: VEGF 165 Antibody (R012) [NBP2-89779] - Measured by its ability to neutralize VEGF165 induced proliferation of human umbilical vein endothelial cells (HUVEC). The Neutralization Titer (IC50) is typically 15-75ng/mL in the presence of 10 ng/mL Recombinant Human VEGF165.

Applications for VEGF 165 Antibody (R012) - Azide and BSA Free

Application
Recommended Usage

Neutralization

Optimal dilutions of this antibody should be experimentally determined.

Formulation, Preparation, and Storage

Purification

Protein A purified

Formulation

0.2 um filtered solution in PBS

Format

Azide and BSA Free

Preservative

No Preservative

Concentration

Please see the vial label for concentration. If unlisted please contact technical services.

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Store at 4C short term. Aliquot and store at -20C long term. Avoid freeze-thaw cycles.

Background: VEGF 165

VEGF (Vascular endothelial growth factor) is the only growth factor that stimulates vascular permeability. It promotes endothelial proliferation and survival, angiogenesis, vasculognesis and inhibits apoptosis. VEGF mitogenic activity is specific for endothelial cell and that makes it distinct among other growth factors. VEGF is thought to be important in the pathophysiology of neuronal and other tumors, by functioning as a promter of angiogenesis for human gliomas. Human VEGF occurs in several molecular variants and the 165 form is the most common form in most tissues. Biological activities of VEGF are not species-specific and glycosylation is not required for biological activity.

Alternate Names

MVCD1, vascular endothelial growth factor A, Vascular permeability factor, VEGF-A, VEGFMGC70609, VPFvascular endothelial growth factor

Gene Symbol

VEGFA

Additional VEGF 165 Products

Product Documents for VEGF 165 Antibody (R012) - Azide and BSA Free

Certificate of Analysis

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Product Specific Notices for VEGF 165 Antibody (R012) - Azide and BSA Free

This product is for research use only and is not approved for use in humans or in clinical diagnosis. Primary Antibodies are guaranteed for 1 year from date of receipt.

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FAQs for VEGF 165 Antibody (R012) - Azide and BSA Free

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  • Q: What is the heparin binding activity of FGF and VEGF?

    A: These proteins are not assayed for their ability to bind Heparin. More information about the FGF family of growth factors is available in this review article: Basilico, C. (1992) Adv. Can. Res. 59:115.

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