WIN 55,212-2 mesylate

Key Product Details

Product Description

WIN 55,212-2 mesylate is a selective high affinity CB₂ agonist (K_i values are 3.3 and 62.3 nM at the human cloned CB₂ and CB₁ receptors respectively).

Product Specifications for WIN 55,212-2 mesylate

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Solubility

Preparing Stock Solutions for WIN 55,212-2 mesylate

The following data is based on the product molecular weight 522.61.

Batch specific molecular weights may vary from batch to batch due to the degree of hydration, which all affect the solvent volumes required to prepare stock solutions.

Select a batch to recalculate based on the batch molecular weight:

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Concentration / Solvent Volume / Mass	1 mg	5 mg	10 mg
1 mM	1.91 mL	9.57 mL	19.13 mL
5 mM	0.38 mL	1.91 mL	3.83 mL
10 mM	0.19 mL	0.96 mL	1.91 mL
50 mM	0.04 mL	0.19 mL	0.38 mL

Calculators

Background References

References are publications that support the biological activity of the product. See our Citations tab to view 85 publications citing the usage of this product.

• Martellotta Self-administration of the cannabinoid receptor agonist WIN 55,212-2 in drug naive mice. Neuroscience 1998 PMID: 9622233
• Felder Comparison of the pharmacology and signal transduction of the human cannabinoid CB₁ and CB₂ receptors. Mol.Pharmacol. 1995 PMID: 7565624
• Griffin Evaluation of cannabinoid receptor agonists and antagonists using the guanosine-5'-O-(3-[35S]thio)-triphosphate binding assay in rat cerebellar membranes. J.Pharmacol.Exp.Ther. 1998 PMID: 9580597
• D'Ambra Conformationally restrained analogues of pravadoline: nanomolar potent, enantioselective, (aminoalkyl)indole agonists of the cannabinoid receptor. J.Med.Chem. 1992 PMID: 1732519

Product Documents for WIN 55,212-2 mesylate