Catalog Number: 3951
Chemical Name: N1,N4-Di-2-pyridinyl-1,4-benzenedimethanamine
Biological Activity
Potent chemokine receptor type 4 (CXCR4) antagonist (EC50 = 0.3 nM). Inhibits CXCR4/stromal cell-derived factor-1 (SDF-1)-mediated modulation of cAMP in vitro (EC50 = 1.2 nM).
Technical Data
  • M.Wt:
  • Formula:
  • Solubility:
    Soluble to 25 mM in DMSO
  • Purity:
  • Storage:
    Store at -20°C
  • CAS No:
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Background References
  1. Discovery of small molecule CXCR4 antagonists.
    Zhan et al.
    J.Med.Chem., 2007;50:5655
  2. Pyridinium N-(2'-azinyl)aminides: regioselective synthesis of N-(2-pyridyl) substituted polyamines.
    Reyes et al.
    Chem.Inform., 2002;34
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