XAF1 Antibody Blocking Peptide

Novus Biologicals | Catalog # NBP1-76615PEP

Novus Biologicals
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Key Product Details

Source

Synthetic

Applications

Antibody Competition
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Product Specifications

Description

A blocking peptide containing Amino acids at the carboxy terminus of human XAF1.

Source: Synthetic

(Accession #: CAA68030)

Application Notes

This peptide is useful as a blocking peptide for NBP1-76615.

For further blocking peptide related protocol, click here.

Protein / Peptide Type

Antibody Blocking Peptide

Formulation, Preparation, and Storage

NBP1-76615PEP
Formulation PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin.
Preservative 0.02% Sodium Azide
Concentration 0.2 mg/ml
Shipping The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage Store at -20C. Avoid freeze-thaw cycles.

Background: XAF1

X-linked inhibitor of apoptosis (XIAP; MIM 300079) is a potent member of the IAP family. All members of this family possess baculoviral IAP (BIR) repeats, cysteine-rich domains of approximately 80 amino acids that bind and inhibit caspases (e.g., CASP3; MIM 600636). XIAP has 3 BIR domains and a C-terminal RING zinc finger that possesses E3 ubiquitin ligase (see MIM 601623) activity. XAF1 antagonizes the anticaspase activity of XIAP and may be important in mediating apoptosis resistance in cancer cells (Liston et al., 2001 [PubMed 11175744]).[supplied by OMIM]

Alternate Names

BIRC4-binding protein, BIRC4BPBIRC4 binding protein, HSXIAPAF1, XIAP associated factor 1, XIAPAF1XIAP-associated factor 1

Gene Symbol

XAF1

Additional XAF1 Products

Product Documents for XAF1 Antibody Blocking Peptide

Certificate of Analysis

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Product Specific Notices for XAF1 Antibody Blocking Peptide

This product is for research use only and is not approved for use in humans or in clinical diagnosis. This product is guaranteed for 1 year from date of receipt.

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