XAP 044

( 1 Review )    
Product Datasheet
Catalog Number:5248
Chemical Name:7-Hydroxy-3-(4-iodophenoxy)-4H-1-benzopyran-4-one
Product Details
Supplemental Products
Reviews
Biological Activity
Potent and selective mGlu7 antagonist (IC50 = 88 nM); inhibits lateral amygdala long term potentiation (LTP) in brain slices from wild type mice. Displays no effects on the LTP of mGlu7 deficient mice. Exhibits novel activity by binding to the mGlu7 Venus flytrap domain (VFTD). Exhibits anti-anxiety effects in rodent models. Brain penetrant.
Technical Data
  • M.Wt:
    380.13
  • Formula:
    C15H9IO4
  • Solubility:
    Soluble to 100 mM in DMSO and to 20 mM in ethanol
  • Purity:
    >98
  • Storage:
    Store at -20°C
  • CAS No:
    196928-50-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
Product Datasheets

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs
Average Rating: 4 (Based on 1 review)

Have you used XAP 044?

Submit a review and receive a $25US/€18/£15/$25CAN amazon gift card if you include an image - $10US/€7/£6/$10CAN Amazon card for reviews without an image. Limited to verified customers in USA, Canada and Europe.

Read what people are saying who have used XAP 044.

We have 1 review tested in 1 species: Human.

Filter by Ratings
Very Good
(1)
All Ratings
Filter by Applications
All Applications
Filter by Species
Human
(1)
All Species

Images Ratings Applications Species Reviewed By Date Details
  Very Good
  Human Anonymous 01/05/2018
Show

Summary

Species Human
Pub Med ID 27769854

Please scroll the above reviews for more
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.

Order Details

Contact Us to Order
reload

Feedback

Customer Information
Calculators

Molarity Calculator

Calculate the mass, volume, or concentration required for a solution.
=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and SDS / CoA (available online).

R&D Systems Guarantee