Z-Cyclopentyl-AP4

   
Product Datasheet
Catalog Number:3249
Chemical Name:cis-(±)-1-Amino-3-phosphonocyclopentane carboxylic acid
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Biological Activity
Group III mGlu receptor agonist that exhibits higher potency at mGlu4 than mGlu8 (EC50 values are 49 and 124 μM respectively) with no activity at mGlu7. Selectively inhibits synaptic activity in the lateral perforant pathway (IC50 values are 130 and 1859 μM in the lateral and medial perforant pathways respectively). Conformationally restrained analog of L-AP4 (Cat No. 0103).
Technical Data
  • M.Wt:
    209.14
  • Formula:
    C6H12NO5P
  • Solubility:
    Soluble to 50 mM in 1.1eq. NaOH
  • Purity:
    >98
  • Storage:
    Store at +4°C
  • CAS No:
    103439-17-4
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis. All Tocris products are intended for laboratory research use only.
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