2 results for "20S Proteasome Small Molecules and Peptides" in Products

20S Proteasome Small Molecules and Peptides

The 20S Proteasome is the catalytic core component of the multi-complex 26S Proteasome that selectively degrades intracellular proteins. It is commonly associated with regulatory complexes, which include the 19S Proteasome, the PA28 alpha/beta complex, or the PA28 gamma complex. The 20S Proteasome is composed of 28 subunits arranged into four stacked rings. The outer rings, containing seven subunits each, are composed of closely-related but non-identical alpha subunits. The amino-terminal tails ...

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Potent irreversible proteasome inhibitor; active in vivo

Alternate Names: PR-171
Chemical Name: S)-α-[[2-(4-Morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide
Purity: ≥98%
Potent irreversible proteasome inhibitor; active in vivo
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Enhancer of 20S proteasome assembly and 20S-mediated protein degradation

Alternate Names: TCH165
Chemical Name: Ethyl (4R,5R)-rel-1-benzyl-5-(4-(benzylamino)phenyl)-2-(4-methoxyphenyl)-4-phenyl-4,5-dihydro-1H-imidazole-4-carboxylate
Purity: ≥98%
Enhancer of 20S proteasome assembly and 20S-mediated protein degradation
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