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APC Products

APC is a ubiquitous, tumor-suppressor protein. APC mutations are common in most colon cancers, generally resulting in a gene product that is truncated in the carboxy terminal region. APC contains several binding domains, including an EB1, DLG (PDZ sequence) and PSD-93 domain that bind to cytoskeletal elements. In addition to beta-catenin degradat...

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Reactivity: Human, Mouse (Negative)
Details: Mouse IgG1 kappa Monoclonal Clone #ALi 12-28
Applications: WB, ELISA, Flow, ICC/IF
Novus Antibodies
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