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Axin-1 Products

Axin-1 is a negative regulator of the Wnt signaling pathway, which is involved in regulation of embryonic axis formation in vertebrates. Axin-1 binds to beta-catenin and glycogen synthase kinase-3 (GSK-3) to promote beta-catenin phosphorylation and subsequent degradation. Axin-1 also binds to the adenomatous polyposis coli (APC) gene, a known tumor...

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Reactivity: Human
Details: Mouse IgG2a Kappa Monoclonal Clone #2B11
Applications: WB, ELISA, ICC/IF, Func
Immunocytochemistry/ Immunofluorescence: Axin-1 Antibody (2B11) [H00008312-M01]
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