Beclin 1 Proteins and Enzymes

Beclin1 (Bcl-2 interacting coiled-coil protein; also know as ATG6) is a 60 kDa member of the Beclin family of proteins. It is part of a lipid-kinase complex that includes UVRAG and PI3 and induces autophagy; in the presence of Bcl-2, autophagy is repressed. Beclin1 is widely expressed but abundantly found in mammary epithelium, glia and neurons. Hu...