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Dkk-4 Products

Dickkopf related protein 4 (Dkk-4) is a member of the Dkk protein family of secreted Wnt antagonists. Dkk-1 and Dkk-4 antagonize Wnt/beta-catenin signaling by direct high affinity binding to the Wnt coreceptor LRP5/6 and inhibiting interaction of LRP5/6 with the Wnt-Frizzled complex. Dkk-1 and Dkk-4 also bind the transmembrane proteins Kremen-1 and...

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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #185709
Applications: WB, ELISA, ELISA(Cap), ELISA(Det)
Novus Antibodies
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