DSCAM Proteins and Enzymes

DSCAM is a member of the Ig superfamily that maps to a region in chromosome 21 associated with Down Syndrome mental retardation. It encodes a 230 kDa type I membrane protein with a large extracellular domain comprising ten C2-type Ig-like domains and six fibronectin type III repeats. Human DSCAM is expressed in axonal and dendritic processes of the...