2 results for "ICAT" in Products

ICAT Products

Human ICAT is a physiological inhibitor of the beta-catenin/Wnt signaling pathway that is found in both cytosol and nucleus. The molecule contains two domains, an alpha-helical N-terminal region, and an acidic, extended C-terminal region. The alpha-helical region binds to beta-Catenin, displacing CBP/p300, while the acidic C-terminus blocks Tcf int...

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Reactivity: Human
Details: Goat IgG Polyclonal
Applications: WB
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Reactivity: Human
Details: Mouse IgG2B Monoclonal Clone #536017
Applications: IHC
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