1 result for "Integrin alpha 2b beta 3" in Products

Integrin alpha 2b beta 3 Products

Integrin alpha 2b beta 3, also known as GPIIbIIIa, is the most abundant Integrin expressed by megakaryocytes and platelets, both on the surface and within alpha granules. Deficiencies of alpha 2b beta 3 produce Glanzmann thrombasthenia, a potentially serious bleeding disorder. Active cell surface alpha 2b beta 3 adheres to Fibrinogen, mediating pla...

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Reactivity: Human
Source: CHO
Accession #: P08514 (Integrin alpha 2b) & AAA52589 (Integrin beta 3)
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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