LILRB4/CD85k/ILT3 Proteins and Enzymes

LILRB4, also known as ILT3, CD85k, and LIR-5, is a transmembrane glycoprotein that is expressed on dendritic cells (DC), monocytes, macrophages, and vascular endothelial cells (EC). Ligation of LILRB4 triggers ITIM-mediated inhibition of cell-activating signaling, leading to enhanced immune tolerance and reduced allogeneic graft rejection. Soluble ...