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Mcl-1 Products

Mcl-1 (Myeloid Cell Leukemia 1) is a member of the Bcl-2 family of proteins. Alternative splicing results in two distinct isoforms: Mcl-1L (long) enhances cell survival by inhibiting apoptosis, while Mcl-1S (short) promotes apoptosis. The elimination of Mcl-1L is an early and required step for DNA damage-induced apoptosis. Degradation of Mcl-1L is ...

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Reactivity: Human
Details: Mouse IgG1 Monoclonal Clone #OTI10F6
Applications: IHC, Flow, ICC/IF
Novus Antibodies
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