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PTP1B Products

Protein tyrosine phosphatase 1B (PTP1B) dephosphorylates tyrosine residues on several proteins including c-Src, beta-catenin, and the receptors for insulin and epidermal growth factor. PTP1B knock-out mice are resistant to high-caloric intake-induced obesity and have exaggerated insulin responses, suggesting that PTP1B may play a role in regulating...

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Reactivity: Human, Rat, Canine, Monkey, Primate
Details: Mouse IgG2A Monoclonal Clone #OTI1D10
Applications: KO, IHC, Flow, ICC/IF
Novus Antibodies
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