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TGF-beta Products

TGF-beta 1 (Transforming Growth Factor beta 1) is a pleiotrophic cytokine that regulates immune function, proliferation, and epithelial-mesenchymal transition. TGF-beta 1 associates with LAP to form a latent complex. It can be is activated from latency by plasmin, matrix metalloproteases, thrombospondin 1, and a subset of integrins. TGF-beta 1 signals through complexes of TGF-beta RII with TGF-beta RI/ALK-5 or ALK-1. TGF-beta signaling is modulated by the accessory receptors TGF-beta RIII/Betaglycan and Endoglin/CD105.

Reactivity: Human, Mouse, Rat, Bovine, Canine, +2 More
Details: Mouse IgG1 kappa Monoclonal Clone #1D11.16.8
Applications: IHC, ELISA, ELISA(Cap), B/N, ICC/IF, + 2 More
Immunohistochemistry: TGF-beta Antibody (1D11.16.8) - Azide and BSA Free [NBP2-47736]
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