1 result for "TIMP-3" in Products
TIMP-3 Products
TIMPs-1 through -4 regulate the activity of zinc metalloproteases known as MMPs, ADAMs and ADAMTSs. Structurally, TIMPs contain two domains. The N-terminal domain binds to the active site of mature metalloproteases via a 1:1 non-covalent interaction, blocking access of substrates to the catalytic site. In addition, The C-terminal domain of TIM...
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #277128 |
| Applications: | Flow, IP, CyTOF-ready |
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